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Fig 1.

Study protocol.

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Fig 2.

Mean time of the study periods (A), and room-air and cooling vest temperature (B). Values are mean ± standard deviation. ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 3.

Resting energy expenditure (A), respiratory quotient (B) and substrate metabolism (C) across study periods. Values are mean ± standard deviation (n = 10). Repeated measures analysis of variance was performed, using Bonferroni post-hoc tests for pairwise comparisons. Common letters show significant differences (P≤0.05) between two specific periods. CHO: carbohydrates, REE: resting energy expenditure, RQ: respiratory quotient, ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 4.

Skin temperature and body gradients across study periods.

Panel (A): skin temperature, Panel (B): proxies of peripheral vasoconstriction in both arms, Panel (C): body and supraclavicular skin temperature gradients. Values are mean ± standard deviation. Repeated measures analysis of variance was performed, using Bonferroni post-hoc tests for pairwise comparisons. Common letters show significant differences (P<0.05) between two specific periods. Symbol * shows significant differences among all periods (P<0.05). ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 5.

Thermal comfort perception measured by visual analogue scales across study periods.

Visual analogue scales measured thermal comfort from “no cold at all” (= 0 mm) to “maximum tolerable cold” (= 100 mm). Values are mean ± standard deviation (n = 11). Repeated measures analysis of variance was performed, using Bonferroni post-hoc tests for pairwise comparisons. Common letters show significant differences between two specific periods (P<0.05). Symbol * shows significant differences among all time periods (P<0.05). ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 6.

Electrical muscle activity (mV) and burst shivering rate (min-1) of eight different muscles across study periods.

Panel (A): root mean square, Panel (B): burst shivering rate. Values are mean ± standard deviation (n = 6). Repeated measures analysis of variance (Bonferroni post-hoc tests) and Friedman test (adjusted significance) were respectively performed for EMG RMS and EMG BSR. Common letters show significant differences between periods (P < 0.05). BSR: burst shivering rate, RMS: root mean square, ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 7.

Tissue saturation index (%) and relative changes in the concentration of total haemoglobin (ΔtHb), oxy-haemoglobin (ΔO2Hb), and deoxy-haemoglobin (ΔHHb) in the abdominal and forearm regions across study periods.

Panel (A): abdominal region, Panel (B): forearm region. Values are mean ± standard deviation (n = 9). Repeated measures analysis of variance was performed, using Bonferroni post-hoc tests for pairwise comparisons. Common letters show significant differences between two specific periods (P<0.05). ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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Fig 8.

Frequency domain parameters of heart rate variability across study periods.

Panel (A): absolute power, Panel (B): normalized power, Panel (C): low frequency—high frequency ratio. Values are mean ± standard deviation (n = 7). Repeated measures analysis of variance was performed, using Bonferroni post-hoc tests for pairwise comparisons. No significant differences were found across study periods (P>0.05). ST: shivering threshold, WP: warm period, 31% and 64%: percentage of the individual’s time exposed to cold until shivering occurred.

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