Fig 1.
The schematic metabolic pathway of tryptophan and kyurenine.
Table 1.
Baseline demographic characteristics and lifestyle factors in pancreatic cancer cases and control subjects, the Shanghai Cohort Study and the Singapore Chinese Health Study.
Table 2.
Median (5th– 95th percentile) values of serum biomarkers of tryptophan, kynurenines and neopterin in pancreatic cancer cases and control subjects, the Shanghai Cohort Study and the Singapore Chinese Health Study.
Table 3.
Beta coefficientsa for tryptophan and kynurenine metabolites derived from linear regression models on smoking status (current or former versus never smokers), cotinine, body mass index (BMI), and pyridoxal 5’-phosphate (PLP) among all controls (N = 362).
Table 4.
Associations of tryptophan, kynurenines, and neopterin with pancreatic cancer risk in both Shanghai and Singapore cohorts combined (187 cases and 362 controls).