Table 1.
Demographic and clinical characteristics of patients carrying the 591, 106, 002 and other ribotypes.
Fig 1.
Multiple correspondence analyses.
Variable categories contributing to dimension 1 (x-axis) and dimension 2 (y axis); variables with major contribution are close to the cero line in the chart. Ten variables contributing to both dimensions are shown.
Fig 2.
Analysis of ribotype 591 by MLVA.
MLVA was applied to 27 isolates belonging to the ribotype 591. Dendrogram showing similarities of banding patterns generated with high-resolution capillary gel-based electrophoresis (CE)-PCR. MLVA clusters are identified by minimum-spanning tree: one clonal complex is defined by a MLVA type with less than a two-locus difference. In addition, free fecal toxin A/B (FFT), toxin in cell culture (TC), presence of PaLoc genes (tcdA/tcdB), minimal inhibitory concentrations (MIC) for vancomycin (VAN), metronidazole (MTZ), moxifloxacin (MOX) and clindamycin (CLIN) are shown for each isolate with the respective breakpoints. VNTR, variable-number tandem repeat.
Fig 3.
Analysis of ribotype 106 by MLVA.
MLVA was applied to 12 isolates belonging to the ribotype 106. Dendrogram showing similarities of banding patterns generated with high-resolution capillary gel-based electrophoresis (CE)-PCR. MLVA clusters are identified by minimum-spanning tree: one clonal complex is defined by MLVA type with less than a two-locus difference. In addition, free fecal toxin A/B (FFT), toxin in cell culture (TC), presence of PaLoc genes (tcdA/tcdB), minimal inhibitory concentrations (MIC) for vancomycin (VAN), metronidazole (MTZ), moxifloxacin (MOX) and clindamycin (CLIN) are shown for each isolate with the respective breakpoints. VNTR, variable-number tandem repeat.
Fig 4.
Analysis of ribotype 002 by MLVA.
MLVA was applied to 11 isolates belonging to the ribotype 002. Dendrogram showing similarities of banding patterns generated with high-resolution capillary gel-based electrophoresis (CE)-PCR. MLVA clusters are identified by minimum-spanning tree: one clonal complex is defined by MLVA type with less than a two-locus difference. In addition, free fecal toxin A/B (FFT), toxin in cell culture (TC), presence of PaLoc genes (tcdA/tcdB), minimal inhibitory concentrations (MIC) for vancomycin (VAN), metronidazole (MTZ), moxifloxacin (MOX) and clindamycin (CLIN) are shown for each isolate with the respective breakpoints. VNTR, variable-number tandem repeat.
Table 2.
Antibiotic resistance profile of C. difficile strains of ribotypes 591, 106 and 002.