Fig 1.
The experimental design (description in the text).
Fig 2.
The influence of cyclophosphamide on the growth of D. magna.
(a) Average ± SD growth rate of Daphnia clones D, N and e S on Day 5, cultured with (grey bars) or without (white bars) cyclophosphamide.
Fig 3.
The influence of cyclophosphamide on the reproduction of D. magna.
Average (± SD) (a) age, (b) size at first reproduction and (c) first neonate number of Daphnia (Clones D, N and S) cultured with (grey bars) or without (white bars) cyclophosphamide. Stars indicate significant differences between the control and experimental groups.
Fig 4.
Common proteins with changed levels in Daphnia animals treated with cyclophosphamide.
A Venn diagram showing common proteins, either (a) up- or (b) down regulated, in Daphnia, which changed significantly (q value < 0.1) in the clone D, N and S individuals which had been treated with cyclophosphamide.
Table 1.
Proteins with changed expressions in the D clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control (C)/CP treated animals).
Table 2.
Proteins with changed expressions in the N clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).
Table 3.
Proteins with changed expressions in the S clone individuals which had been treated with CP, compared to control individuals, with q-value < 0.1 (ratio = control/CP treated animals).