Fig 1.
The summary of exclusion criteria for UNOS dataset.
(a) Patients, (b) Features.
Fig 2.
Illustration of ToPs construction.
Fig 3.
Tree of predictors for 3-year post transplantation survival (End nodes shaded gray. 3 most relevant features shown for each node as feature indices).
Table 1.
Comparisons among ToPs/R, existing clinical risk scores, regression methods, and machine learning benchmarks for post-transplantation survival prediction using C-index and AUC (at horizons of 3-months, 1-year, 3-years, and 10-years).
Table 2.
Comparisons among ToPs/R, regression methods, and machine learning benchmarks for pre-transplantation survival prediction using C-index and AUC (at horizons of 3-months, 1-year, 3-years, and 10-years).
Fig 4.
Calibration graphs for post-transplantation (ρ = Root mean square error).
Fig 5.
Calibration graphs for pre-transplantation (ρ = Root mean square error).
Fig 6.
Venn diagram of clinical features used for each clinical risk score.
(a) Post-transplantation, (b) Pre-transplantation.
Table 3.
Comparison of C-index among ToPs/R, existing clinical risk scores, and the best machine learning benchmark for survival prediction in post-transplantation with different feature sets.
Fig 7.
Kaplan-Meier survival curves for different periods in post- and pre- transplantation.
Table 4.
Comparisons among ToPs/R, existing clinical risk scores, regression methods, and machine learning benchmarks for post-transplantation survival prediction using C-index and AUC (at horizons of 3-months, 1-year, and 3-years).
Train on 2005-2009; predict on 2010-2015.
Table 5.
Comparisons among ToPs/R, regression methods, and machine learning benchmarks for pre-transplantation survival prediction using C-index and AUC (at horizons of 3-months, 1-year, and 3-years).
Train on 2005-2009; predict on 2010-2015.
Fig 8.
(a) Informative features for each cluster for 3-month pre-transplantation survival prediction, (b) 3-year pre-transplantation survival prediction, (c) for 3-month post-transplantation survival prediction, (d) for 3-year post-transplantation survival prediction, (e) for pre-transplantation survival across the time horizon, (f) for post-transplantation survival across the time horizon.
(a ∼ f: from top left to bottom right).