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Fig 1.

Flow diagram of the study selection process.

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Table 1.

Characteristics of participants in included studies of tooth loss in relation to risk of coronary heart disease and stroke.

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Table 2.

Outcomes and covariates of included studies of tooth loss in relation to risk of coronary heart disease and stroke.

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Table 2 Expand

Fig 2.

Forest plots for meta-analysis of tooth loss and risk of cardiovascular disease.

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Fig 3.

Dose-response relationship between tooth loss and risk of cardiovascular disease.

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Table 3.

Stratified analyses of relative risk of coronary heart disease and stroke.

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Table 3 Expand

Fig 4.

Forest plots for meta-analysis of tooth loss and risk of stroke.

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Fig 5.

Dose-response relationship between tooth loss and risk of stroke.

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Fig 5 Expand