Fig 1.
Flow diagram of selection strategy.
Flow diagram depicting the selection strategy for trials used in this meta-analysis. 12 RCTs finally met our criteria. RCT = randomized clinical trials.
Table 1.
Characteristics of trials.
Fig 2.
RR of CIN for comparison of iodixanol with LOCM in diabetic patients.
Forest plot of risk ratios (RR) for the incidence of contrast-induced nephropathy (CIN) for comparison of iodixanol with low-osmolar contrast media (LOCM). CIN was defined as an increase of more than 25%, or 0.5 mg/dL (44.2 μmol/L), or either, in serum creatinine level (SCr), respectively. LOCM low-osmolar contrast medium/media; CI confidence interval; M-H Mantel-Haenszel method.
Fig 3.
RR of CIN for comparison of iodixanol with iohexol or other non-iohexol LOCM.
Funnel plot of studies for contrast-induced nephropathy (CIN) for comparison of iodixanol with iohexol or other non-iohexol LOCM in diabetic patients.
Fig 4.
Funnel plot for the association between contrast use and CIN under different definitions of CIN.