Table 1.
Characteristics of patients included in the study.
Fig 1.
Delta values of different subsets of CD4 T-cells after long-term follow up, in cART naïve (boxes in light grey) and in cART (boxes in dark grey) groups of patients.
Delta values of subsets defined by CD45RA, KI67 and CD31 markers are shown in the upper row graph. Delta values of PD1 and Tim3 expression in subsets defined according to CD45RA and CD31 markers are shown in the middle row graph. Delta values of CD95 and CD57 expression on subsets defined according to CD31 and Ki67 markers are shown in lower row graph. Delta values significantly different from zero are marked with an asterisk.
Fig 2.
Delta values of different subsets of CD8 T-cells after long-term follow up, in cART naïve (boxes in light grey) and in cART (boxes in dark grey) groups of patients.
Delta values of subsets defined by HLADR and CD38 markers are shown in the upper row graph. Delta values of PD1 and Tim3 expression in subsets defined according to HLADR and CD38 markers are shown in the lower row graph. Delta values significantly different from zero are marked with an asterisk.
Fig 3.
Box-plot graphs showing the delta values of different CD4 and CD8 T-cell subsets after long-term follow up in the cART naïve group of HIV patients.
Patients were stratified according to the significance of their individual CD4 slope during follow up into two groups: those without (light grey boxes) and with (dark grey boxes) a significant CD4 slope. p-values for the comparison between groups (Mann-Whitney test) are given.
Fig 4.
Scatter-plot graphs showing the association between variation of CD4 counts (Δ CD4 counts) and variation of immune parameters after long-term follow up (ΔLT) in patients on cART.
Spearman Rho (σ) coefficient and p-value are shown in each scatter plot.