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Fig 1.

Data selection flow.

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Table 1.

Demographic and disease specific data of people with MS (n = 23 studies).

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Table 2.

Overview of included studies.

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Table 3.

Relations between SD and psychological and neuropsychological measures.

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Table 4.

Treatment effects for SD and psychological measures in intervention studies.

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Table 5.

CASP quality assessment for case control studies.

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Table 6.

CASP quality assessment for cohort studies.

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Table 7.

CASP quality assessment for intervention studies.

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