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Fig 1.

The overall proportions of subjects in each chronic kidney disease (CKD) stage (3a: eGFRcr 45–59 ml/min/1.73 m2; 3b: eGFRcr 30–44 ml/min/1.73 m2; 4: eGFRcr 15–29 ml/min/1.73 m2; 5: eGFRcr <15 ml/min/1.73 m2).

The difference in proportions of subjects in each CKD stage was examined using chi-squared test (the non-sarcopenia group vs. the sarcopenia group). Although the proportion of subjects with advanced CKD stages seemed to be higher in the sarcopenia group than in the non-sarcopenia group, no statistically significant difference was observed (P-value 0.078).

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Fig 1 Expand

Fig 2.

The overall proportions of subjects using any class of diuretic in each CKD stage.

The differences between the proportions of subjects using any class of diuretic in each CKD stage were examined using chi-squared test (non-diuretic use vs. diuretic use) followed by a post hoc Bonferroni’s correction for comparisons between CKD stages. The proportions of subjects using any class of diuretic were higher in advanced CKD stages (stage 4, 5) (P-value <0.05).

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Fig 2 Expand

Fig 3.

The overall proportions of subjects using each class of diuretic.

The differences in proportions of subjects using each class of diuretic were examined using chi-squared test. The proportion of subjects treated with any class of diuretic was higher in the sarcopenia group (P-value 0.001). When different classes of diuretic were analyzed, the proportion of subjects treated with loop diuretics was higher in the sarcopenia group (P-value <0.001).

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Fig 3 Expand

Table 1.

Demographics and clinical characteristics of 260 elderly patients with NDD-CKD.

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Table 1 Expand

Table 2.

Data of anthropometric measurements and physical function in 260 elderly patients with NDD-CKD.

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Table 2 Expand

Table 3.

Unadjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD.

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Table 3 Expand

Table 4.

Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for overall diuretic use).

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Table 4 Expand

Table 5.

Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for loop diuretic use).

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Table 5 Expand

Table 6.

Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for CKD stage and overall diuretic use).

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Table 6 Expand

Table 7.

Adjusted odds ratios for sarcopenia in 260 elderly patients with NDD-CKD (adjusted for CKD stage and loop diuretic use).

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Table 7 Expand