Table 1.
Clinical features of conjunctival naevi (total number of naevi = 57).
Table 2.
Anterior segment optical coherence tomography (AS-OCT) features of conjunctival naevi (total number of naevi = 57).
Table 3.
Comparison of anterior segment optical coherence tomography (AS-OCT), ultrasound biomicroscopy (UBM) and slit-lamp (SL) examinations in naevus margin visualization, in the detection of intralesional cysts and in posterior naevus shadowing in 21 conjunctival naevi (21 eyes).
Table 4.
Results of histological examination of the excised naevi (n = 24).
Epithelial layer thickness above the naevus was measured on anterior segment optical coherence tomography images before surgical excision.
Fig 1.
Localization of conjunctival naevi: Bulbar (A), caruncular (B), plical (C), intermarginal (D).
Fig 2.
Clinical appearances of conjunctival naevi are extremely variable.
Anterior segment pictures of amelanotic and cystic (A), moderately pigmented and cystic (B), small, strongly pigmented (C) and giant juvenile (D) conjunctival naevi.
Fig 3.
Clinico-morphological features (A, C, E, G) and anterior segment optical coherence tomography (AS-OCT; B, D, F, H) of conjunctival naevi.
Pigmented lesion (A) without cystic alterations on AS-OCT (B). Amelanotic naevus with macroscopically visible cysts (C), which are confirmed with AS-OCT examination (D). Small pigmented conjunctival naevus: cystic alterations cannot be visible on slit-lamp examination (E), intralesional cysts can be detected only with AS-OCT (F). Pigmented conjunctival naevus: intralesional cysts can be visualized both with slit-lamp examination (G) and with AS-OCT (H).
Fig 4.
Comparison of anterior segment optical coherence tomography (AS-OCT, left column: A, D, G, J) and ultrasound biomicroscopy (UBM, right column: C, F, I, L) for imaging conjunctival naevi.
Middle column: clinical eppearane of the naevi (B, E, H, K). Intralesional morphology of pigmented bulbar naevi (B, E) can be depicted on AS-OCT examinations in more details (A, D) compared to UBM examinations (C, F). In contrast, highly pigmented caruncular (H) and bulbar naevi (K) can be completely visualized only with UBM examinations (I, L), as severe shadowing limits the usefulness of AS-OCT (G, J).
Fig 5.
Subepithelial conjunctival naevus: anterior segment optical coherence tomography (AS-OCT) (A); histopathological appearance (B, hematoxylin-eosin, x10) and clinical appearance (C). Junctional conjunctival naevus: AS-OCT feature (D); result of histopathological examination (E, hematoxylin-eosin, x10); clinico-morphological appearance (F).
Table 5.
Conjunctival naevi, eye colour, and the presence of iris freckles and naevi.
Total number of eyes with naevus = 57.