Table 1.
Baseline characteristics and outcomes of the 205 patients with sepsis.
Fig 1.
Time course of platelet count and absolute immature platelet count (AIPC).
Platelet count and AIPC were measured from admission (day 1) to day 7 in patients with sepsis, classified into four groups according to nadir platelet count during the 7 days: severe thrombocytopenia (nadir platelet count ≤40×103/μL); moderate thrombocytopenia (41–80×103/μL); mild thrombocytopenia (81–120×103/μL); and normal-increased platelet count (>120×103/μL). Data are expressed as mean with the 95% confidence interval shown by the error bars. Multiple analysis of variance was among the four groups.
Fig 2.
Box plot showing (a) platelet and (b) absolute immature platelet count (AIPC).
Platelet count and AIPC on the day of admission (day 1) and at the nadir during the 7 days are shown. Septic patients were classified into four groups according to nadir platelet count during the first 7 days of their ICU stay: severe thrombocytopenia (nadir platelet count ≤40×103/μL); moderate thrombocytopenia (41–80×103/μL); mild thrombocytopenia (81–120×103/μL); and normal-increased platelet counts (>120×103/μL). Multiple pairwise comparison used the Steel–Dwass test.
Fig 3.
Time course of coagulation biomarkers from admission (day 1) to day 7 in patients with sepsis.
Septic patients were classified into four groups according to nadir platelet count during the first 7 days of their ICU stay: severe thrombocytopenia (nadir platelet count ≤40×103/μL); moderate thrombocytopenia (41–80×103/μL); mild thrombocytopenia (81–120×103/μL); and normal-increased platelet counts (>120×103/μL). Data are expressed as mean with the 95% confidence interval shown by the error bars.
Table 2.
Univariate/multivariate logistic regression models for severe thrombocytopenia development (nadir platelet count <40×103/μL).
Table 3.
Univariate and multivariate Cox regression models to predict 28-day mortality.