Fig 1.
Gender data with colour coding for the University of Michigan and UC Davis laboratories: (a) boxplots; (b) RLE plot.
Fig 2.
(a) additive effects only; (b) additive effects only, in two batches; (c) additive and non-additive effects; (d) additive and non-additive effects, in two batches.
Fig 3.
Gender data: Removing additive and non-additive sample effects.
(a) RLE plot of the gender data with the additive sample effect removed; (b) RLE plots of the gender data with the additive and successive non-additive sample effects removed, i.e. for p = 1, …, 6.