Table 1.
Characteristics of the 179 patients.
Fig 1.
76y old patient with prostate cancer Gleason score 7, treated 5 years ago by high intensity focused ultrasound (HIFU).
Serum PSA level at the time of FCH PET/CT 9.1ng/mL. FCH PET/CT revealed isolated FCH uptake by two lobes of prostate but no foci evocative of regional of distant prostate cancer recurrence. Scheduled palliative medical treatment was replaced by radiation therapy with curative intent. Adequacy of this therapeutic decision was confirmed by clinical follow-up, serum PSA level 11 months after FCH PET/CT = 0.8 ng/mL.
Fig 2.
64y old patient with prostate cancer Gleason score 8 treated 6 years ago by radical prostatectomy.
PSA serum level at the time of FCH PET/CT 3.5 ng/mL. Intense FCH uptake by left external iliac lymph node evocative of prostate cancer recurrence. Scheduled watchful waiting replaced by complete androgen blockade leading to complete remission of disease according to follow-up data.
Fig 3.
68y old patient with prostate cancer Gleason score 7 treated 1 year ago by radical prostatectomy.
Serum PSA level at the time of FCH PET/CT 2.4ng/mL; On FCH PET/CT equivocal focus in the right prostate loge and left pulmonary lesion evocative of malignancy. Scheduled androgen deprivation therapy was replaced by watchful waiting and 4 months later, by radiation therapy on prostate loge. Pulmonary lesion was resected and histology confirmed poorly differentiated large cell lung cancer with visceral pleural invasion.
Table 2.
Results of reading of FCH PET/CT (L = local recurrence inside prostate bed, RLN = regional lymph nodes, D = distant metastases or second primaries).
Table 3.
Impact on patient management: Treatment scheduled before and then in view of FCH PET/CT.
Table 4.
Frequency of impact on patient management according to previous treatment(s).
Table 5.
Clinical impact of FCH PET/CT in biochemical recurrence of prostate cancer: Comparison and pooling with the results of other studies (An impact corresponds to a change in patient management induced by the results of FCH PET/CT; percentage values have been rounded).