Fig 1.
Flowchart of the MEF simulation in the 3D model of the contracting ventricle.
The dashed arrow shows the implementation of mechanical feedback in the model.
Table 1.
Numerical values of the parameters in the SAC formulation.
Fig 2.
3D fiber-based geometrical model of the contracting ventricle (a) before and (b) after contraction. The LV (red line) denotes the outer boundary (circumference) of the ventricle.
Fig 3.
Stretch effects on the simulated APs at different degrees of steady-state stretch (λ = 1.10 to 1.30).
Fig 4.
Comparison of the ATs influenced by different preload lengths (stretch ratio λ = 1.00, 1.10, 1.15, 1.20, and 1.25).
AT–activation time.
Fig 5.
Comparison of the RTs influenced by the different preload lengths (stretch ration λ = 1.00, 1.10, 1.15, 1.20, and 1.25).
RT–recovery time.
Fig 6.
Time course of the simulated APs (A) and the corresponding PV loops (B) under control and HF conditions.
Table 2.
Comparison of the APD at different degrees of stretch under normal and HF conditions.