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Table 1.

Cell viability and cytotoxicity grade for freshly mixed materials in MTT assay (n = 5).

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Fig 1.

X-ray diffraction (XRD) patterns of the novel root-end filling material (NRFM) and novel radio-opaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr).

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Fig 1 Expand

Fig 2.

FTIR spectra of the novel root-end filling material (NRFM) and novel radio-opaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr).

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Fig 2 Expand

Fig 3.

Setting time (A) and compressive strength (B) of novel root-end filling material (NRFM), novel radio-opaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr) and glass ionomer cement (GIC). Different letters indicate significant differences between the five materials (one-way ANOVA followed by Fisher’s LSD test, P<0.05).

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Fig 3 Expand

Fig 4.

Washout resistance test of novel root-end filling material (NRFM), novel radio-opaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr) and glass ionomer cement (GIC) in phosphate-buffered solution (PBS).

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Fig 4 Expand

Fig 5.

pH values of novel root-end filling material (NRFM), novel radiopaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr) and glass ionomer cement (GIC) at various time intervals.

Different letters indicate significant differences between the five materials (two-way ANOVA followed by Fisher’s LSD test, P<0.05).

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Fig 5 Expand

Fig 6.

Radio-opacity samples of novel root-end filling material (NRFM) (A), novel radio-opaque root-end filling materials (NRFM-Ba (B), NRFM-Bi (C), NRFM-Zr (D)), glass ionomer cement (GIC) (E), dentin (F) and aluminium step-wedge (G).

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Fig 6 Expand

Table 2.

Means and standard deviations of contact angle of all materials (n = 5).

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Table 2 Expand

Fig 7.

Solubility of novel root-end filling material (NRFM), novel radiopaque root-end filling materials (NRFM-Ba, NRFM-Bi and NRFM-Zr) and glass ionomer cement (GIC) at various time intervals.

Different letters indicate significant differences between the five materials (two-way ANOVA followed by Fisher’s LSD test, P<0.05).

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Fig 7 Expand

Table 3.

Cell viability and cytotoxicity grade for set materials in MTT assay (n = 5).

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Table 3 Expand

Fig 8.

ALP activity of NRFM-Zr, GIC and negative control at various time intervals.

Different letters indicate significant differences between them (two-way ANOVA followed by Fisher’s LSD test, P<0.05).

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Fig 8 Expand

Fig 9.

Alizarin red staining of novel root-end filling material with zirconium dioxide (A), negative control group (B) and glass ionomer cement (C). Scale bar = 100 μm.

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Fig 9 Expand