Table 1.
Questionnaire elements for case-control study.
Table 2.
Distribution of ethnicity/origin across controls and patients with Kawasaki disease (KD).
Table 3.
Habitual environmental exposures in children with Kawasaki disease (KD).
Fig 1.
Clinical signs and symptoms in the weeks preceding the onset of Kawasaki disease (KD).
Fig 2.
Time series (5-day moving averages) and cross-correlation of new cases of Kawasaki disease (KD) vs. count of biological atmospheric particles for lag-times of 0 to 25 days for the following types of particles: Pollen, trees (all trees and deciduous trees only reported separately), grasses, weeds and myxomycetes.
Upward triangles indicate maximum and downward triangles minimum cross-correlations. The difference between lowest and peak correlation was statistically significant for all types other than grasses.
Fig 3.
Time series (5-day moving averages) and cross-correlation of new cases of Kawasaki disease (KD) vs. count of biological atmospheric particles for lag-times of 0 to 25 days for spores and fungi (ascomycetes, basidiomycetes and fungi imperfecti separately).
Upward triangles indicate maximum and downward triangles minimum cross-correlations. The difference between lowest and peak correlation was statistically significant only for ascomycetes but the overall patterns was conserved for all types.
Fig 4.
Composite analysis of wind patterns for months with high and low Kawasaki disease (KD) occurrences.
Time series of standardized monthly number of KD cases, with months (May-October in grey) and anomalously high and low occurrences of new KD cases highlighted in red and blue, respectively (A). Wind speed (color, units [m/s]) and direction (arrows) during months with high KD occurrences (B), low KD occurrences (D) and difference between months with high and low KD occurrences (C) centered over the Pacific Ocean.
Table 4.
Factors associated with global distribution of Kawasaki disease (KD) (model R2: 0.84, p<0.001).
Fig 5.
Conceptual framework for individual risk of developing Kawasaki disease (KD) linking disease etiology, pathogenesis and global distribution.