Fig 1.
Fig 1A and 1B. MSTs of 746 B. hyodysenteriae isolates (n = 741 from pigs; n = 5 from birds and mice) from the MLST database and from this study.
MST A mirrors the spatial distribution of isolates. Each circle represents a different sequence type (n = 186), the color indicates the country of origin and the size reflects the number of isolates deposited. MST B depicts the temporal distribution of isolates. Each circle represents a different year of isolation and the size reflects the number of isolates from the year in question. Clonal complexes (CC) of STs sharing at least six common loci are indicated by grey shading. The predicted founder of a CC is marked with an asterisk (*); # = CCs with unclear founders.
Table 1.
Minimum inhibitory concentration of pleuromutilins used in this study and classification of isolates as being resistant, intermediate or susceptible.
Table 2.
Single nucleotide polymorphism in the B. hyodysenteriae ribosomal protein L3 gene/protein in relation to sequence type and pleuromutilin susceptibility.
Table 3.
Patterns of virulence-associated genes (VAGs) in 116 B. hyodysenteriae field isolates from pigs in Germany.
Table 4.
MIC50* values of pleuromutilins for B. hyodysenteriae isolates of major multilocus sequence types according to the year of isolation.