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Fig 1.

Decision tree.

Decision tree showing the decision tree pathways in the people with body and tail of pancreatic cancer who underwent distal pancreatectomy.

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Table 1.

Parameters used in the model and their source.

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Table 2.

Results of deterministic analysis (per patient).

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Table 2 Expand

Table 3.

Results of probabilistic sensitivity analysis (per patient).

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Fig 2.

Scatter plot of incremental cost per incremental quality-adjusted life year.

The scatter plot shows that the points lie almost symmetrical about the X-axis, i.e. the costs were similar between laparoscopic and open distal pancreatectomy, but most points lie to the right of the Y-axis, i.e. laparoscopic distal pancreatectomy was associated with increased quality-adjusted life years (QALYs).

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Fig 3.

Cost-effectiveness acceptability curve.

The cost-effectiveness acceptability curve shows that the probability laparoscopic distal pancreatectomy was cost-effective compared to open distal pancreatectomy was 70% to 80% at the willingness-to-pay thresholds generally used in England (£20,000 to £30,000 per QALY gained).

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Fig 4.

Univariate sensitivity analysis (Tornado diagram).

The tornado diagram shows that there is significant uncertainty in the results, especially with regards to mortality.

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Table 4.

Results of probabilistic sensitivity analysis (per patient) (scenario analysis 1).

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Table 5.

Results of probabilistic sensitivity analysis (per patient) (scenario analysis 2).

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