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Fig 1.

PRISMA diagram.

The figure displays the information retrieval process for valuable articles and exclusion process of irrelative articles for this research.

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Table 1.

Characteristics of included studies.

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Table 1 Expand

Fig 2.

Forest plot of pooled relative risk for one-year OS from eligible studies.

The area of each square represents the weighting, and the positions of each square demonstrate the risk ratio point estimate. Horizontal lines represent 95% confidence interval (CI). M-H = Mantel-Haenszel. Events = patients died from any cause within one year.

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Fig 2 Expand

Fig 3.

Forest plot of pooled relative risk for three-year OS from eligible studies.

The area of each square represents the weighting, and the positions of each square demonstrate the risk ratio point estimate. Horizontal lines represent 95% confidence interval (CI). M-H = Mantel-Haenszel. Events = patients died from any cause within three years.

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Fig 3 Expand

Fig 4.

Forest plot of pooled relative risk for five-year OS from eligible studies.

The area of each square represents the weighting, and the positions of each square demonstrate the risk ratio point estimate. Horizontal lines represent 95% confidence interval (CI). M-H = Mantel-Haenszel. Events = patients died from any cause within five years.

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Fig 4 Expand

Fig 5.

Forest plot of pooled relative risk for three-year DFS from eligible studies.

The area of each square represents the weighting, and the positions of each square demonstrate the risk ratio point estimate. Horizontal lines represent 95% confidence interval (CI). M-H = Mantel-Haenszel. Events = recurrence or metastasis happened within three years.

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Fig 5 Expand

Fig 6.

Funnel plots for publication bias of one-year OS (a), three-year OS (b), five-year OS (c), and three-year DFS (d).

The vertical line indicates the pooled estimate of the overall risk ratio, with the sloping lines representing the expected 95% CI for a given standard error.

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Fig 6 Expand