Fig 1.
The iron content in two different meals (A and B) was labeled with either 55Fe or 59Fe. Meal A contained no lactobacilli and was served on morning 1 and 2, whereas meal B, which contained 1010 cfu lyophilised Lp299v, was served on morning 3 and 4. Ten to 14 days after the meals were administered, blood samples were drawn and the radiation from the two Fe isotopes were determined. Directly after drawing the blood sample a reference dose (3 mg 59Fe-labeled iron (II) + 30 mg of ascorbic acid dissolved in 10 mL of 0.01 M HCl) was administered. The following morning yet another identical reference dose was served. After a further 10–14 days the daily mean absorption from the two reference doses was analysed in blood samples.
Table 1.
Study subject data for study 1 and 2.
Fig 2.
Study flowchart.
Fig 3.
Iron absorption from a meal administered together with capsules with or without Lactobacillus plantarum 299v (Lp299v).
Fig 3A: Study 1 (n = 14). Fig 3B: Study 2 (n = 28). The bars illustrate mean iron absorption and the whiskers cover the standard deviation (SD), and the dots illustrate individual subject data. Paired two-sample Student’s t-test was used to analyze differences between meals with or without Lp299v. Data were log-transformed before statistical analysis. Abbreviations: cfu, colony forming units.
Table 2.
Iron absorption from a meal administered together with capsules with or without Lactobacillus plantarum 299v (Lp299v).