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Fig 1.

Flow chart of the study sample.

DHEAS, dehydroepiandrosterone-sulfate; SHBG, sex hormone-binding globulin; Anatomical Therapeutic Chemical Classification System Code for Urologicals: LO2B and for Testosterone-5-alpha-reductase-inhibitors: G04CB.

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Fig 2.

MRI post-processing figure depicting the fat quantification pipeline.

Subcutaneous adipose tissue is highlighted red, visceral adipose tissue is highlighted green, other fat tissue is highlighted yellow.

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Table 1.

Baseline characteristics of the study population, stratified by sex.

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Table 2.

Association between sex hormones and anthropometry in men and women.

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Table 2 Expand

Fig 3.

Associations of sex hormones with leptin.

Analysis of testosterone, estrone, androstendione, and dehydroepiandrosterone-sulfate (DHEAS) with body-mass-index (BMI) and leptin among men (upper part) and women (lower part). Linear regression adjusted for age, sex, smoking, physical activity, type 2 diabetes mellitus, hypertension, and cholesterol.

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Fig 4.

Associations of sex hormones with BMI and leptin levels.

Estimated means of the body-mass-index (BMI) and leptin by tertiles of testosterone, estrone, androstenedione, and dehydroepiandrosterone-sulfate (DHEAS). Analysis of variance was adjusted for adjusted for age, sex, smoking, and physical activity.

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Fig 4 Expand