Fig 1.
Driving pressure and total pressure dependent outflow as a function of intraocular pressure, for a range of values of α (note: is 1 microlitre/min/mm Hg).
Fig 2.
Average outflow facility as a function of intraocular pressure and for a range of values of α.
Fig 3.
Local (or point) outflow facility Cp as a function of intraocular pressure and for a range of values of α.
These curves may be calculated either using Eq (27), or by taking the derivative with respect to IOP of the total pressure dependent outflow curves shown in Fig 1.
Fig 4.
Driving pressure and pressure dependent outflow as a function of intraocular pressure, for a range of values of α.
Pressure dependent outflows are calculated using Eq (18) with a normotensive pressure of 15 mm Hg as the intraocular reference pressure. The data in this figure can employed to help understand or evaluate Eqs (23) and (24).
Fig 5.
Average outflow facility , as a function of intraocular pressure and for a range of values of α.
The average outflow facility is calculated using Eq (28). Note: the average outflow facility curves shown in the figure above are not the same as the average outflow facility curves shown in Fig 2, as the pressure range over which averaging occurs are different in the two figures. For example for α equal to 0.05, at 20 mm Hg the average outflow facility in the above figure is just over 0.4 microlitres/minute/mm Hg, while in Fig 2 it is about just under 0.6 microlitres/minute/mm Hg. The relative difference in the two average outflow facilities increases with increasing α.
Fig 6.
Average outflow facility as a function of intraocular pressure and for a range of values of α.
These average facility curves are calculated using Eq (26), but wrongly assumes pT is equal to zero, when in fact pT equals 3 mm Hg.
Fig 7.
Driving pressure and total pressure dependent outflow as a function of intraocular pressure, and for a range of values of α.
The driving pressure (p − pref) is calculated using Eq (14) with pT equal to zero.
Table 1.
Data employed for ‘first-principles’ estimation of pT and αcon, which describe the no-flow IOP and the rate of decrease in local pressure dependent outflow via the conventional route.
Table 2.
Estimates of model parameters (estimated range in brackets), and total pressure dependent outflow at 15 mm Hg.