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Fig 1.

Flow chart of patients’ outcome in the study.

Patients were first divided according to whether they fulfilled or not KCH criteria and therefore were listed or not for liver transplantation. Reasons for liver transplant ineligibility and the outcome of the different categories were reported. ALF: Acute Liver Failure; KCH: Kings College criteria.

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Fig 1 Expand

Table 1.

Baseline characteristics of population study.

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Table 1 Expand

Table 2.

Comparison between not-transplanted (NOLT) and transplanted (LT) patients (RFH cohort).

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Table 2 Expand

Table 3.

Performance of main prognostic scores in predicting 3-month mortality in not-transplanted (NOLT) and transplanted (LT) patients (RFH cohort).

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Table 3 Expand

Table 4.

Cox regression analysis of pre-transplant variables associated with 3-month mortality in not-transplanted group.

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Table 4 Expand

Fig 2.

ALF OFs score characteristics.

(a) ROC curves for ALF-OFs, CLIF-C OF and KCH for 3-month mortality in not-transplanted patients. (b) Kaplan Meier curve of ALF-OFs score for 3-month mortality in not-transplanted patients.

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Fig 2 Expand

Table 5.

Comparison between patients who died within 48 hours after LT and those that survived.

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Table 5 Expand

Fig 3.

ROC curves for ALF-OFs, CLIF-C OF and KCH for patients at high risk of futility following liver transplantation.

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Fig 3 Expand

Fig 4.

Scatter plot showing the cut-off values of ALF-OFs score for liver transplant in acetaminophen-related acute liver failure.

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Fig 4 Expand