Fig 1.
Representative images of echocardiographic assessment of right ventricular systolic function.
(A) %RVFS [(a–b)/a × 100%]; (B) percentage RV area change [(a–b)/a × 100%]; (C) TAPSE; (D) right ventricular MPI [(a–b)/b]; and (E) TVlat. See text for further information on how these indices were obtained or calculated. LA, left atrium; LV, left ventricle; RA, right atrium; RV, right ventricle. Reprinted from J Am Soc Echocardiogr. 2012 Mar;25(3):280–6, Takahiro Sato et al., Validation study on the accuracy of echocardiographic measurements of right ventricular systolic function in pulmonary hypertension,[7] with permission from Elsevier.
Table 1.
Baseline patient characteristics.
Table 2.
Demographics and baseline right heart catheterization and cardiac magnetic resonance imaging data of PAH and non-PAH patients.
Table 3.
Clinical parameters and treatment regimens for pulmonary hypertension at baseline and follow-up.
Table 4.
Associations of the five echocardiographic parameters with cardiac magnetic resonance imaging-derived right ventricular ejection fraction (N = 54).
Fig 2.
Correlation between the changes in CMRI-derived RVEF and echocardiographic parameters.
There were significant correlations between the changes in CMRI-derived RVEF and those in the five echocardiographic indices. %RV area changes at baseline and follow-up were not calculated in two patients (one PAH, one non-PAH) because of poor image quality, whereas the other four echocardiographic indices were evaluated in all 54 patients. CMRI, cardiac magnetic resonance imaging; RV, right ventricular; RVEF, right ventricular ejection fraction; RVFS, right ventricular fractional shortening; TAPSE, tricuspid annular plane systolic excursion; RV MPI, right ventricular myocardial performance index; TVlat, systolic lateral tricuspid annular motion velocity.
Fig 3.
Receiver operating characteristic curve analysis of the accuracy of echocardiographic parameters to detect a significant improvement in CMRI-derived RVEF.
%RV area changes at baseline and follow-up were not calculated in two patients (one PAH, one non-PAH) because of poor image quality, whereas the other four echocardiographic indices were evaluated in all 54 patients. CMRI, cardiac magnetic resonance imaging; RV, right ventricular; RVEF, right ventricular ejection fraction; RVFS, right ventricular fractional shortening; TAPSE, tricuspid annular plane systolic excursion; RV MPI, right ventricular myocardial performance index; TVlat, systolic lateral tricuspid annular motion velocity.
Table 5.
Diagnostic performance of echocardiographic indices to detect significant improvement in CMRI-derived RVEF.