Table 1.
Grading system for Adrenal Pheochromocytoma and Paraganglioma (GAPP).
Fig 1.
Immunohistochemical (IHC) staining of succinate dehydrogenase gene subunit B (SDHB).
(A) Positive SDHB IHC staining with definite granular cytoplasmic staining (mitochondrial pattern) and (B) negative SDHB IHC staining without definite granular cytoplasmic staining, in contrast to positive staining in the internal controls such as endothelial cells (arrow) and sustentacular cells (SDHB IHC original magnification, ×400).
Table 2.
Baseline characteristics of the 72 PPGL patients according to the occurrence of metastasis.
Table 3.
Baseline characteristics of the 72 PPGL patients according to the occurrence of metastasis by PHEO or PGL.
Table 4.
Association of the individual parameters of the GAPP at the initial operation with occurrence of metastasis.
Table 5.
Association of the individual parameters of the M-GAPP at the initial operation with occurrence of metastasis.
Table 6.
Comparison of the GAPP score, PASS, and M-GAPP score for predicting metastatic potential in PPGL.
Table 7.
Receiver-operating characteristic analyses of three scoring systems for predicting metastatic potential in pheochromocytoma and paraganglioma.
Fig 2.
Metastasis-free survival analyses according to the Grading system for Adrenal Pheochromocytoma and Paraganglioma (GAPP) score, Pheochromocytoma of the Adrenal Scaled Score (PASS), and modified GAPP (M-GAPP) score at the initial operation.
Fig 3.
Correlation of the Grading system for Adrenal Pheochromocytoma and Paraganglioma (GAPP) score, Pheochromocytoma of the Adrenal Scaled Score (PASS), and modified GAPP (M-GAPP) score at baseline with the time (months) to metastasis after the initial operation.