Table 1.
Mean (±SD) milk and serum pharmacokinetic parameters after intramammary administration of ceftiofur hydrochloride in healthy (HQ) and infected quarters (IQ) in healthy and infected cows.
Table 2.
Mean (±SD) milk pharmacokinetic parameters after intramammary administration of ceftiofur hydrochloride in healthy and infected quarters with high, mid and low milk production.
Fig 1.
Milk concentration in nine healthy lactating cows' quarters with high (n = 11), mid (n = 12) and low (n = 10) production after eight infusions of ceftiofur hydrochloride at 24-h intervals, 125 mg/quarter, into all four quarters, plotted with MIC 90 (0.25 μg/mL).
Fig 2.
Milk concentration in nine infected lactating cows' quarters with high (n = 10), mid (n = 10) and low (n = 11) production after eight infusions of ceftiofur hydrochloride at 24-h intervals, 125 mg/quarter, into all four quarters, plotted with MIC 90 (0.25 μg/mL).
Fig 3.
Mean-serum concentration (±SD) in healthy (n = 3) and infected (n = 3) cows administered eight intramammary infusions of ceftiofur hydrochloride at a dose of 125 mg/quarter each 24 h.
Arrows indicate time of daily infusion of ceftiofur into all four quarters.