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Fig 1.

Four primary MR sequences of a 2D GBM slice highlighting different intra-tumoral structures over (a) T1, (b) T1C, (c) T2, and (d) FLAIR, along with (e) composite label map.

The bottom row depicts the delineated (a) solid core of the tumor (maroon), (b) enhancing core (green) and necrotic core (yellow), (c-d) whole tumor (blue).

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Fig 2.

Saliency maps for High-grade glioma samples.

MR slice numbers: 13, 19, 35, 46, 67, 81, 100, 121 (left to right) by (a) FLAIR, (b) T2, and (c) T1C sequences. (d) Saliency maps generated in 2D [5].

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Fig 2 Expand

Fig 3.

3D saliency maps.

(a) Ground truth, with saliency map generated (b) using Ref. [5] and (c) the proposed method PR.

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Fig 3 Expand

Fig 4.

Schematic illustrating voxel-level computation in algorithm PR.

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Fig 4 Expand

Fig 5.

Comparative study over varying thresholds [0-255] on saliency map for HG and LG tumour images.

(a) Precision-Recall, and (b) ROC curves.

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Fig 5 Expand

Fig 6.

3D saliency maps for four HG glioma patients.

(a) Ground truth, with 3D saliency map generated by (b) BA [5], and (c) algorithm PR.

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Fig 7.

3D saliency maps for four LG glioma patients.

(a) Ground truth, with 3D saliency map generated by (b) BA [5], and (c) algorithm PR.

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Fig 7 Expand