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Fig 1.

Schematic diagram showing the microcosm setup for isolation of hypha-associated bacteria from soil.

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Fig 2.

Visualization of P. bilaii hyphal growth and hyphal viability.

Glass cover slips were recovered from soil microcosms at day 0, 4, 6 and 8. Column A: Calcofluor White M2R was used to stain the cell walls of P. bilaii. Columns B, C and D: FUN 1 stain was used to determine metabolically active (B) or inactive (D) hyphae, as well as active and inactive spores (C). Killed hyphae were set as a negative control (Column D, Day 0). All images were obtained at 630 times magnification.

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Fig 3.

Colonization of Penicillium bilaii hyphae by bacteria after incubation for A: 6 days and B: 8 days in soil.

Hyphae and bacteria were stained by SYBR Green and the microscopy image was obtained at 400 times magnification.

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Fig 4.

Composition of microbial communities in A: Bulk soil or B and C: Attached to the hyphae of P. bilaii.

Relative abundances of taxa are shown on phylum level in panel A and B (Proteobacteria are displayed at the class level), while panel C depicts the distribution of proteobacterial genera from the hyphae-associated community. “Others” represent taxa with < 1% relative abundance. Data for either microbial community is obtained from two replicates.

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Fig 5.

Neighbor-joining tree of bacteria associated with P. bilaii hyphae belonging to the genus Burkholderia.

The tree was constructed from 375 unambiguously aligned nucleotides from the V3-V4 regions of the 16S rRNA gene. Sequences derived from hyphae-associated bacteria from the microcosms are designated OTU HB. Bootstrap values are based on 1000 pseudo-replications, and only values > 50% are shown.

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