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Fig 1.

Randomization and follow-up of study subjects.

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Fig 2.

Experimental design—Assessments and interventions on each patient.

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Table 1.

Baseline epidemiological and clinical characteristics according to treatment group.

Values are given as mean (SD) or frequency (percentage) (n = 40).

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Table 1 Expand

Fig 3.

Comparisons of the pain scores in the Visual Analogue Scale (VAS) between s-tDCS and a-tDCS groups pre-treatment and in the postoperative cumulative pain scores (VAS D0-D1).

Error bars indicate standard error of the mean (S.E.M.). Letters indicates a significant difference between the sham group and tDCS group (P < 0.05) assessed by t-test for independent sample.

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Fig 4.

Visual Analogue Scale (VAS 0–10) scores at baseline and during follow-up.

Fig A presents pain on VAS during rest and Fig B, pain on VAS during walking. Error bars indicate standard error of the mean (SEM). Asterisks (*) positioned above symbols indicate significant differences (p<0.01) at those time points using Bonferroni’s test. B0 = baseline. B1 = moment before surgery. D (0–7) = postoperative days.

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Table 2.

Change on NPS(0–10) during CPM-task and B-PCP:S score.

Data area presented as median and interquartile (Q)25-75, mean (SD) and Δ-value (n = 40).

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Fig 5.

A and B. Scatter plots of CSF BDNF and Δ-B-PCP:S score value (i.e., follow-up end minus baseline level) according to s-tDCS (5A) and a-tDCS (5B).

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