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Table 1.

Patient characteristics clinicopathological variables and their prognostic variables for BF, CF and PCD (univariate analysis; log-rank test) (N = 535).

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Fig 1.

Representative immunohistochemical staining for Ki-67.

(A) Gleason grade group 1 (3+3) with Ki-67 <1–2.5%; (B) Gleason grade group 3 (4+3) with Ki-67 <1–2.5%; (C) Gleason grade group 3 (4+3) with Ki-67 2.6–4%; (D) Gleason grade group 4 (4+4) with Ki-67 ≥ 5; (E) Gleason grade group 5 (4–5) with Ki-67 2.6–4; (F) Picture showing the different Ki-67 expression of nuclear staining, varying from negative to strong.

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Fig 2.

Survival analysis for Ki-67 and mitotic count in primary tumors.

(Kaplan-Meier method). Number of events/number of cases are given in parenthesis. (A) Digital scoring; (B) Visual scoring.

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Table 2.

Multivariate analyses (Cox regression, backward conditional) of Ki67 levels and significant clinicopathological variables.

(n = 535). Digital scoring method.

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Table 2 Expand

Table 3.

Multivariate analyses (Cox regression, backward conditional) of Ki67 levels and significant clinicopathological variables.

(n = 535). Visual scoring method.

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Table 3 Expand