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Table 1.

Summary of pupil light reflex parameters and ocular characteristics between patients with optic neuritis and nonarteritic anterior ischemic optic neuropathy in the acute phase and controls.

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Fig 1.

Comparison of pupillary constriction ratio (A), constriction latency (B), average constriction velocity (C), and average dilation velocity (D) between patients with optic neuritis (ON) and nonarteritic ischemic optic neuropathy (NAION). (A, C, D) Pupillary constriction ratio, average constriction velocity, and average dilation velocity revealed no significant difference between the ON group and NAION group. (P values = 0.069, 0.585 and 0.869, respectively). (B) However, constriction latency was significantly delayed in patients with ON compared to NAION (P = 0.047).

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Fig 2.

Comparison of pupillary constriction ratio (A), constriction latency (B), average constriction velocity (ACV) (C), and average dilation velocity (ADV) (D) among patients with acute and chronic phases of optic neuritis (ON), nonarteritic ischemic optic neuropathy (NAION) and normal controls. In the ON group, all these four PLR parameters improved in the chronic phase compared to those in the acute phase (all P < 0.05). On the contrary, there were no significant differences of four parameters between acute and chronic phases in the NAION group.

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Table 2.

Factors associated with pupillary constriction ratio in the acute phase.

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Table 2 Expand

Table 3.

Factors associated with pupillary constriction latency in the acute phase.

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Table 3 Expand