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Table 1.

Search strategy.

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Fig 1.

Flowchart of literature search.

RCT, randomized controlled trial. NACT, neoadjuvant chemotherapy followed by interval debulking surgery. PDS, primary cytoreductive surgery.

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Fig 2.

The quality assessment for selected randomized controlled trials.

Low risk of bias (green circles), unclear risk of bias (yellow circles) and high risk of bias (red circles).

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Table 2.

Details of included studies.

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Table 2 Expand

Fig 3.

Post-operative complications and mortality.

NACT: neoadjuvant chemotherapy followed by interval debulking surgery. PDS: primary cytoreductive surgery.

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Fig 4.

Fatigue and role functioning at cycle 6 and 6-month follow-up.

NACT, neoadjuvant chemotherapy followed by interval debulking surgery; PDS, primary debulking surgery.

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Fig 5.

Emotional functioning and cognitive functioning at cycle 6 and 6-month follow-up.

NACT, neoadjuvant chemotherapy followed by interval debulking surgery; PDS, primary debulking surgery.

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Fig 5 Expand

Fig 6.

Extent of residual disease.

NACT: neoadjuvant chemotherapy followed by interval debulking surgery. PDS: primary debulking surgery.

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Fig 6 Expand