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Table 1.

Composition of the different groups and etiology of liver disease.

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Table 2.

Performance in neuropsychological tests and results of biochemical determinations.

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Fig 1.

Localization of gray matter atrophy between groups including gender as nuisance covariate.

All results were assessed at p<0.05 FWE cluster-corrected for the multiple comparisons in a combination with a threshold of p<0.001 at the uncorrected voxel level. HC, Healthy Controls; nMHE, patients without Minimal Hepatic Encephalopathy; MHE, patients with Minimal Hepatic Encephalopathy; GM, Gray Matter. Images are in neurological convention.

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Table 3.

Areas showing significant gray matter (GM) volume differences between groups including gender as nuisance covariate.

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Table 3 Expand

Table 4.

Correlations between GM volume and cognitive and biochemical variables.

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Fig 2.

Differences among groups in the resting-state functional connectivity (rs-FC) networks including gender as a nuisance variable.

All results were assessed at p<0.05 FWE cluster-corrected for the multiple comparisons in a combination with a threshold of p<0.001 at the uncorrected voxel level. HC, Healthy Controls; nMHE, patients without Minimal Hepatic Encephalopathy; MHE, patients with Minimal Hepatic Encephalopathy; DMN, Default Mode Network; LFPN, Left Fronto Parietal Network; DAN, Dorsal Attentional Network; SN, Salience Network; BGN, Basal Ganglia Network. Images are in neurological convention.

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Fig 2 Expand

Table 5.

Differences among groups in the resting-state functional connectivity (rs-FC) networks including gender as a nuisance variable.

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Table 5 Expand

Table 6.

Correlations among resting-state functional connectivity (rs-FC) networks and cognitive and biochemical variables.

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Table 6 Expand