Table 1.
Participant characteristics according to presence or absence of all-cause mortality and CVD hospitalization end-points.
Table 2.
Age and sex-adjusted rates of all-cause mortality and CVD hospitalization by quartile of serum lipids.
Fig 1.
Age and sex-adjusted rates ratios for all-cause mortality and CVD hospitalization by serum lipid levels.
Models are adjusted for age, sex, smoking status (never, former, current), obesity (no, yes), diabetes (no, yes), hypertension (no, yes), chronic kidney disease (no, yes), anti-hypertensive medication (no, yes), glucose lowering medication (no, yes), lipid-lowering medication (no, yes). Models for specific lipid biomarkers have been additionally adjusted as follows: 1) Total-cholesterol is further adjusted by HDL ≤ 40 for men and ≤ 50 for women (no, yes); 2) HDL-cholesterol is further adjusted by LDL.C ≥ 130 mg/dL (no, yes); 3) Non-HDL-cholesterol is further adjusted by HDL ≤ 40 for men and ≤ 50 for women (no, yes); 4) LDL-cholesterol is further adjusted by HDL ≤ 40 for men and ≤ 50 for women (no, yes); 5) Non-HDL minus LDL-cholesterol is further adjusted by HDL ≤ 40 for men and ≤ 50 for women (no, yes) and LDL-C ≥ 130 mg/dL (no, yes); 6) Triglycerides is further adjusted by total cholesterol > 200 mg/dL (no, yes) and HDL ≤ 40 for men and ≤ 50 for women (no, yes); 7) Total cholesterol/HDL is further adjusted by total cholesterol (mg/dL); and 7) Triglycerides/HDL is further adjusted by total cholesterol (mg/dL).
Table 3.
Rate differences after a 5-year follow-up by altered lipid levels.
Table 4.
Population attributable risk (95% CI) for all-cause mortality and CVD hospitalization by altered lipid levels.
Fig 2.
Proportion of patients with low HDL-cholesterol, including those with isolated low HDL-cholesterol.
Comparison between Australian, Asian and Spanish cohorts. Completed from Huxley RR et al. Circulation. 2011;124:2056–2064) (M = Male; F = Female). Isolated low HDL-cholesterol: patients with normal levels of triglycerides and LDL-Cholesterol.