Fig 1.
P0 denotes no inspiratory pause. P10 and P30 denote the static inspiratory pause of 10 and 30% of the inspiratory time respectively. OLA denotes open lung approach. PEEP ARMA denotes the positive end expiratory pressure titrated according to the PEEP table from the study [5].
Table 1.
Respiratory variables of eight animals during the ventilatory modes studied.
Fig 2.
Respiratory variables during the ventilatory modes tested with eight animals.
Panel A shows the PaCO2 variation during the experiments. Panel B shows the tidal volume per kg. Panel C shows the plateau pressure. Panel D shows the driving pressure. VT denotes tidal volume and RR respiratory rate. The whiskers denote the P10th and P90th. P0 denotes the phase without an inspiratory pause. P10 and P30 denote the static inspiratory pause of 10 and 30% of the inspiratory time respectively. RM denotes recruitment maneuver; * Student-Newman-Keuls’ post-hoc analysis, P < 0.05 vs VT = 6 mL/kg; & Student-Newman-Keuls’ post-hoc analysis, P < 0.05 vs all others.
Fig 3.
Regional ventilation (upper and lower distribution of air) of animals measured through the electrical impedance tomography during the ventilatory modes studied showing the tidal volume per kg of the upper and lower regions during the various frequencies studied.
VT, RR, denote tidal volume, respiratory rate, respectively. P0 denotes the phase without an inspiratory pause. P10 and P30 denote the static inspiratory pause of 10 and 30% of the inspiratory time respectively. RM denotes recruitment maneuver. The whiskers denote the P10th and P90th. Hatched boxes are the gravitational dependent (lower) region. Non-hatched boxes are the non-gravitational dependent (upper) regions. § Wilcoxon`s test, P < 0.008 (Bonferroni’s correction for multiple comparisons) vs lower; ¶ Student-Newman-Keuls’ post-hoc analysis, P < 0.05 vs HFPPV = 60 w/ RM.
Table 2.
Hemodynamic and metabolic variables of eight animals during the ventilatory modes studied.