Fig 1.
The pathology of FPV and CPV-2b experimental infection in cats.
A: Virus shedding in inoculated cats. B: Viral replication in tissues of inoculated cats that were euthanized on 5 dpi. C: Histological examination of infected cat jejunums.
Fig 2.
The difference of miRNA expression levels.
A: Statistical significance of the differences in FPV infection in jejunums is showed in the volcano plot. The top right corner shows the number of differentially expressed miRNAs. B: Statistical significance of the differences in CPV infection in jejunums is showed in the volcano plot. The top right corner shows the number of differentially expressed miRNAs. Distributions of up-regulated (C) and down-regulated (D) miRNAs in FPV and CPV infection. The data depicted here is derived from one cat in each of the three groups.
Table 1.
Summary of differentially expressed levels miRNA in FPV infection and CPV infection group.
According to the descending order of the log2FC value of FPV vs Control.
Fig 3.
KEGG pathways of target genes of differentially expressed miRNAs.
A: Metabolism-related pathways. B: Cytokine- and pathogen-host interaction-related pathways. C: Pathology and cellar structure-related pathways. D: Other pathways.
Fig 4.
The JAK-STAT signaling pathway.
A: The interaction network of the miRNAs, target genes, and JAK-STAT signaling pathway. B: Diagram of the JAK-STAT signaling pathway from the KEGG database. The red blocks mark the regulated genes.