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Table 1.

Patient backgrounds by glaucoma severity.

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Fig 1.

Wide-field en-face SS-OCT image of the inner limiting membrane, showing our method to measure the RNFLD angle.

A: Original B-scan image with the ILM highlighted in green. B: The image aligned to the ILM. C: Method of measuring the angle of the RNFLD in the en-face flattened image.

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Fig 2.

RNFLD angle in different layers.

En-face images of horizontal planes at different depths below the ILM, and measurement of the RNFLD angle in each image. (A) En-face image 1 was averaged from the ILM plane down to 18.2 μm. (B) En-face image 2 was averaged at the range of 20.8 to 36.4 μm from ILM plane. (C) En-face image 3 was averaged at the range of 39.0 to 54.6 μm from ILM plane. (D) Boxplot showing the RNFLD angle in each en-face image. Boxplot is of RNFLD angles for each depth across the entire population.

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Fig 3.

RNFLD angle at different stages of glaucoma.

Boxplot showing the RNFLD angle in the en-face images at different depths in different glaucoma stages. E, M, S mean Early, Moderate, Severe stage. *: p<0.05, **: P<0.01.

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Fig 4.

Association between RNFLD angle and the visual field.

Scatter plot showing the correlation coefficient between RNLDA and HFA MD in the en-face image 1 (A), en-face image 2 (B), and en-face image 3 (C). (D-F) Correlation between RNFLDA and inferior TD. (G-I) Correlation between RNFLDA and superior TD.

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Fig 5.

Association between RNFLD angle and cpRNFLT.

Scatter plot showing the correlation coefficient between RNLDA and cpRNFLT in the en-face image 1 (A), en-face image 2 (B), and en-face image 3 (C). (D-F) Correlation between RNFLDA and cpRNFLT in the inferior hemifield. (G-I) Correlation between RNFLDA and cpRNFLT in the superior hemifield.

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Fig 6.

Association between RNFLD angle and wrgc.

Scatter plot showing the correlation coefficient between RNLDA and wrgc in the en-face image 1 (A), en-face image 2 (B), and en-face image 3 (C).

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