Fig 1.
Salient craniofacial differences between AMH and Neanderthals (top) and between dogs and wolves (bottom).
Fig 2.
Graphical representations of overlapping genes showing signatures of positive selection in AMH and domesticated species.
(a) Hypergeometric distributions for each group (individual domesticated species and the domesticate pool) with the probability of the intersection size found with AMH (v). cat: v = 15, p = 0.1454; dog: v = 15, p = 0.0293; cattle: v = 9, p = 0.0028; horse: v = 7, p = 0.122; dom: v = 41, p = 0.0034 (see S4 Table for details). (b) Venn diagram with the number of genes with signatures of positive selection overlapping between AMH and domesticated species. The number in each (sub)set is the number of genes showing signatures of positive selection shared by AMH and the respective species (see Table 1 and S2 Table for details). (c) Graph displaying the overlapping genes showing evidence of positive selection in AMH and one or more domesticated species (n = 41), and genes with evidence of positive selection in two or more domesticates (but not AMH) (n = 9) (see S1–S3 Tables for details).
Table 1.
List of 41 overlapping genes with evidence of positive selection in AMH and domesticated species (for more details, see S2 Table).
Fig 3.
Examples of synteny analysis for 3 genes showing signatures of positive selection in AMH and domesticated species.
Genes of interest (DCC, GRIK3 and BRAF) and their 3 flanking protein-coding genes are shown in AMH, cattle, horse, dog and cat, illustrating their conserved syntenies. For other genes, see S6 Table.