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Fig 1.

Preliminary work and general procedure of this study.

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Table 1.

CUMS schedule.

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Fig 2.

Results of the body weight of rats submitted to 6-week CUMS (mean ± SD, n = 40).

**p < 0.01 vs control.

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Fig 3.

Results of sucrose preference of rats submitted to 6-week CUMS(mean ± SD, n = 40).

A: 1 h sucrose preference(%); B: 12 h sucrose preference(%); C: 24 h sucrose preference(%). *p < 0.05, **p < 0.01 vs control.

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Fig 4.

Results of the coat status test of rats submitted to 6-week CUMS (mean ± SD, n = 40).

**p < 0.01 vs control.

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Table 2.

Results of horizontal movement, rearing, grooming behaviors, feces, latency (sec), total scores in the open-field test of rats submitted to 6-week CUMS (mean± SD, n = 40).

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Fig 5.

Results of the percentage of time and entries in the open arms in elevated plus-maze test of rats submitted to 6-week CUMS (mean ± SD, n = 40).

A: Time spent in open arms(%); B: Entries of open arms(%).**p < 0.01 vs control.

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Fig 5 Expand

Fig 6.

Results of the latency and time of grooming behavior following a 10% sucrose solution spray in the splash test of rats submitted to 6-week CUMS(mean ± SD, n = 40).A: Grooming latency(sec); B: Grooming time(%).

**p < 0.01 vs control.

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Fig 7.

Results of forced swimming test of rats submitted to 6-week CUMS (mean ± SD, n = 40).

**p < 0.01 vs control.

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Fig 8.

Results of latency of Morris water maze test of rats in initial spatial training(mean ± SD, n = 40).

**P < 0.01 vs control.

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Table 3.

Results of the latency and the times of passing in the MWM test of rats submitted to 6-week CUMS (mean ± SD, n = 40).

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Table 4.

Variables entered and inclusion parameters.

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Table 5.

Standardized discriminant function coefficients.

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Table 6.

The assessment effect of discriminant functions.

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Table 7.

Results of Pearson correlation coefficients (N = 40, Prob > |r| under H0: Rho = 0).

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