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Fig 1.

Flow diagram of the study selection process.

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Table 1.

Characteristics of the included studies.

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Table 2.

Potential HI-related risk factors for PVL.

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Fig 2.

Fixed-effect model forest plot of the odds ratio of the association between oligohydramnios and PVL.

The pooled OR of oligohydramnios is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 3.

Fixed-effect model forest plot for the odds ratio of the association between acidemia and PVL.

The pooled OR of acidemia is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 4.

Forest plot of the odds ratio of the association between low Apgar score and PVL.

A random-effect model was used to assess the association between low Apgar score at 1 minute and PVL. A fixed-effect model was used to assess the association between low Apgar score at 5 minutes and PVL. The pooled OR of low Apgar score is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 5.

Fixed-effect model forest plot of the odds ratio of the association between apnea and PVL.

The pooled OR of apnea is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 6.

Fixed-effect model forest plot of the odds ratio of the association between RDS and PVL.

The pooled OR of RDS is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 7.

Fixed-effect model forest plot of the odds ratio of the association between seizures and PVL.

The pooled OR of seizures is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 8.

Fixed-effect model forest plot of the odds ratio of the association between preeclampsia/eclampsia and PVL.

The pooled OR of preeclampsia/eclampsia is presented as a solid diamond at the bottom of the forest plot, the width of which represents the 95% CI.

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Fig 9.

Funnel plot for publication bias test.

The two oblique lines indicate the pseudo 95% confidence limits.

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