Fig 1.
Flow diagram of the study selection process.
Table 1.
Main methodological characteristics of the Old World leishmaniasis studies.
Table 2.
Main methodological characteristics of the New World leishmaniasis studies.
Table 3.
Characteristics of the population enrolled in the Old World leishmaniasis studies.
Table 4.
Characteristics of the population enrolled in the New World leishmaniasis studies.
Table 5.
Outcomes in Old World leishmaniasis studies.
Table 6.
Outcomes in New World leishmaniasis studies.
Table 7.
MA intralesional therapy schedules among Old World leishmaniasis studies.
Table 8.
Intralesional antimoniate pentavalent therapy schedules among New World leishmaniasis studies.
Fig 2.
The pooled efficacy rate of Sbv intralesional therapy in New and Old Worlds CL studies.
Fig 3.
Initial response (A), initial cure (B) and definite cure (C) rates with Sbv intralesional therapy in Old World leishmaniasis studies.
Fig 4.
Meta-analysis of studies comparing IL-Sbv directly with topical and physical therapeutic alternatives.
Fig 5.
Initial response (A) and initial cure (B) rates with Sbv intralesional therapy in New World leishmaniasis studies.
Fig 6.
Meta-analysis of studies comparing IL-Sbv directly with IL-Sbv plus cryotherapy: a sensitivity analysis.