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Fig 1.

Age and sex distribution of the study sample.

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Fig 1 Expand

Fig 2.

Mid-sagittal CBCT evaluation of spheno-occipital synchondrosis while the head in the default orientation.

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Fig 2 Expand

Fig 3.

Mid-sagittal CBCT images demonstrating the spheno-occipital synchondrosis closure Stages.

Stage 0, unfused. Stage 1, fusing endocranially. Stage 2, fusing ectocranially. Stage 3, complete fusion.

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Fig 3 Expand

Table 1.

Definition of the staging system used for scoring spheno-occipital synchondrosis closure degree.

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Table 1 Expand

Table 2.

Inter and intra-observer reliability.

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Table 2 Expand

Fig 4.

Correlation between age and spheno-occipital synchondrosis closure in males (n = 361) and females (n = 380).

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Table 3.

Descriptive statistics for spheno-occipital synchondrosis closure in study population.

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Table 3 Expand

Fig 5.

Distribution of study population according to age, sex, and spheno-occipital synchondrosis closure Stage (median and quartile range).

See Table 3 for data.

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Fig 5 Expand

Fig 6.

Males and females spheno-occipital synchondrosis closure rate per year (percentage).

The Scatterplot with nonlinear fit curve and 95% CI shows the data from Table 7 and Table 8.

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Fig 6 Expand

Table 4.

Simple least square regression output for spheno-occipital synchondrosis closure.

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Table 4 Expand

Table 5.

Regression output for spheno-occipital synchondrosis closure in relation to age.

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Table 5 Expand

Table 6.

Age ranges for modern individuals based on regression analysis probability distribution (PI, prediction interval).

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Fig 7.

Means and SD of spheno-occipital synchondrosis closure rate per year (percentage) in males and females, see Table 7 and Table 8 for data.

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Fig 7 Expand

Table 7.

Spheno-occipital synchondrosis closure rate in males (percentage / year) between 9–16 years.

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Table 7 Expand

Table 8.

Spheno-occipital synchondrosis closure rate in females (percentage / year) between 9–16 years.

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Table 9.

Menarche commencement distributions among spheno-occipital synchondrosis closure stages.

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Table 9 Expand