Table 1.
Patient characteristics.
Fig 1.
Representative electrophoresis.
Low-resolution gel (1.2%) of plasma from a patient with Impella® support (marked lane) compared to other plasma samples. Very large VWF multimers are missing, large multimers are reduced.
Fig 2.
Course of VWF:CB / VWF:Ag ratio.
Significant reduction of VWF:CB / VWF:Ag ratio during Impella® support—and normalization after cessation of left ventricular unloading. n = 12, *p<0.05 vs pre / post Impella® therapy.
Fig 3.
Characteristic electrophoresis at different time points.
Characteristic low-resolution gel (1.2%) of a patient with Impella®: Very large multimers are absent and large multimes are reduced during microaxial pump support. Existence / recovery of large multimers is documented before and after mechanical left ventricular unloading. The right lane illustrates a characteristic trace of a plasma sample from a healthy person.
Table 2.
Diagnostics of von Willebrand syndrome.