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Fig 1.

Flowchart outlining the number of admissions included and children in the study.

ADR: adverse drug reaction. NOTE: the term "off-label" was defined as the use of drugs that are contraindicated for a given age range, based on information available in the Drugs.com [15].

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Fig 1 Expand

Table 1.

Assessment of severity using the Hartwig severity scale.

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Table 2.

Univariate and multivariate analysis by categorical time invariant risk factor.

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Table 2 Expand

Fig 2.

Cumulative hazard ratio curves by categorical time invariant risk factor by: (a) prior history of ADR of the patient, (b) meglumine antimonate use, (c) antibacterial use and (d) antiepileptic drug use.

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Fig 2 Expand