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Fig 1.

Seasonal distribution of 719 iGAS cases in Germany (2009–2014).

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Fig 2.

Age distribution of iGAS disease in Germany per 100,000 inhabitants per age group per year from 2009 to 2014 (n = 719) based on a population of 80,767,463 in 2013 (http://www.destatis.de).

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Table 1.

Underlying conditions, diagnoses and clinical complications among iGAS cases in Germany (2009–2014).

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Table 1 Expand

Table 2.

Distribution of emm types and superantigen/toxin genes among the 719 iGAS-cases in Germany (2009–2014).

Bold print indicates a statistically-significant positive association from univariate logistic regression analysis (p≤0.05) between the listed emm type and superantigen gene(s).

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Table 2 Expand

Table 3.

Yearly distribution of emm types in 719 iGAS isolates from Germany.

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Table 3 Expand

Table 4.

Multivariate logistic regression results for underlying conditions and risk factors among iGAS cases with reported underlying conditions in Germany (2009–2014).

Bold values indicate a statistically significant association in multivariate analysis.

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Table 4 Expand

Table 5.

Multivariate logistic regression results for clinical complications among 719 iGAS cases in Germany (2009–2014).

Bold values indicate a statistically significant association in multivariate analysis.

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Table 5 Expand

Table 6.

Multivariate logistic regression results for diagnoses of 719 iGAS cases in Germany (2009–2014).

Bold values indicate a statistically significant association in multivariate analysis.

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Table 6 Expand