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Fig 1.

Patient flow chart.

PFT, pulmonary function test.

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Fig 1 Expand

Table 1.

Baseline patient characteristics, n = 95.

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Table 1 Expand

Fig 2.

Proportion of Fabry patients with bronchial obstruction over time.

All values on y-axis are presented as percentage of patients with bronchial obstruction which was defined as FEV1/FVC < 70%.

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Fig 2 Expand

Fig 3.

Proportion of Fabry patients with bronchial obstruction over time, divided by sex.

All values on y-axis are presented as percentage of patients with bronchial obstruction which was defined as FEV1/FVC < 70%.

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Fig 3 Expand

Fig 4.

Proportion of Fabry patients with bronchial obstruction over time, divided by cigarette smoking.

All values on y-axis are presented as percentage of patients with bronchial obstruction which was defined as FEV1/FVC < 70%.

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Fig 4 Expand

Fig 5.

Unadjusted FEV1 changes in Fabry patients over time.

All measures on y-axis are displayed in percent of the predicted values.

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Fig 5 Expand

Fig 6.

Unadjusted FVC changes in Fabry patients over time.

All measures on y-axis are displayed in percent of the predicted values.

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Fig 6 Expand

Fig 7.

Unadjusted DLCO changes in Fabry patients over time.

All measures on y-axis are displayed in percent of the predicted values.

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Fig 7 Expand

Table 2.

Results of generalized linear mixed models for pulmonary obstruction with random intercept and slope for each patient.

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Table 2 Expand

Table 3.

Comparative FEV1 slopes.

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Table 3 Expand