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Fig 1.

Flowchart of the study selection process for the meta-analysis.

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Table 1.

Characteristics of the 12 included studies in this meta-analysis.

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Table 2.

Data extraction from the 12 included studies in this meta-analysis.

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Table 3.

Data extraction from the 12 included studies in this meta-analysis.

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Table 4.

The Newcastle-Ottawa Scale (NOS) quality assessment of the included studies in this meta-analysis.

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Fig 2.

Risk of neonatal congenital malformations between different groups.

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Fig 3.

Risk of neonatal congenital malformations between different groups with exposure only during pregnancy.

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Table 5.

The summary outcomes of this meta-analysis (including those of sensitivity analysis).

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Table 6.

The summary outcomes of this meta-analysis with exposure only during pregnancy.

(including those of sensitivity analysis).

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Table 7.

GRADE for outcomes of this meta-analysis.

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Table 8.

GRADE for outcomes of this meta-analysis.

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Table 9.

GRADE for outcomes of this meta-analysis with exposure only during pregnancy.

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Table 10.

GRADE for outcomes of this meta-analysis with exposure only during pregnancy.

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