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Table 1.

Patient data (Permissive hypercapnia cohort).

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Fig 1.

Blood gas result, ventilation parameters, and number of blood gases of the cohort of immunocompromised children (n = 38) ventilated with allowance of severe hypercapnia.

Dashed line = survivors; solid line = non-survivors. Median and interquartile ranges are given.

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Fig 1 Expand

Fig 2.

Survival and length of ventilation of a cohort of immunocompromised 38 children exposed to severe permissive hypercapnia.

(A) Survival plot and (B) length of ventilation. Dashed line = survivors; solid line = non-survivors.

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Fig 2 Expand

Table 2.

Adverse events (Permissive hypercapnia cohort).

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Table 2 Expand

Table 3.

Long term outcome (Permissive hypercapnia cohort).

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Table 3 Expand

Table 4.

Comparison of the recent permissive hypercapnia period with a historical period.

All admissions of immunocompromised patients to the PICU.

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Table 5.

Comparison of the recent permissive hypercapnia period with a historical period.

Patients ventilated ≥24h*.

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Fig 3.

Comparison of the permissive hypercapnia period (Cohort A) with a historical period (Cohort B).

(A) Survival plots of all episodes of admission of immunocompromised children to the PICU. (B) Survival plots of immunocompromised children ventilated >24h. Solid line = Permissive hypercapnia cohort; dashed line = historical cohort.

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Fig 3 Expand