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Fig 1.

CONSORT flow diagram of the clinical study.

Patient enrollment and outcomes.

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Table 1.

Demographics and baseline characteristics of the patients.

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Table 2.

Changes from baseline in relative insulin response (L/pmol) over the 12-week treatment period.

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Table 2 Expand

Table 3.

Glucose levels (mmol/L) pre-ingestion (0 minute) and changes from pre-glucose ingestion values at 30 and 120 minutes during the OGTT.

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Table 3 Expand

Table 4.

Insulin (pmol/L) levels pre-glucose ingestion (0 minute) and changes from pre-glucose ingestion values at 30 and 120 minutes during the OGTT.

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Table 4 Expand

Table 5.

Changes from lead-in period (baseline) in mean blood home glucose levels (mmol/L) over the 12-Week treatment period.

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Table 6.

Changes from baseline in anthropometric and metabolic parameters at Week 12.

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